The changes up-front - for the match that will be broadcast live on SuperSport at 19h00 - sees Tijde Visser pack down at tighthead prop, while Ewan Coetzee replaces Mzwanele Zito at lock, and Gideon van der Merwe (pictured above) takes over at flank, which sees Carl Els move to the back of the scrum.
There were also three personnel changes in the backline where former SA Schools flyhalf Tinus de Beer gets a run in place of the experienced George Whitehead, and wingers Enver Brandt and Daniel Kasende take over from Eduan Keyter and Ederies Arendse respectively.
Whitehead's unavailability, due to injury, means Stefan Ungerer will take over the captaincy from his halfback partner.
Both teams are still winless in 2021, with Tafel Lager Griquas having gone down against the DHL Stormers and Cell C Sharks, while the Elephants suffered defeats against the Lions and Vodacom Bulls.
Tafel Lager Griquas: 15 Masixole Banda, 14 Daniel Kasende, 13 Michal Haznar, 12 Andre Swarts, 11 Enver Brandt, 10 Tinus de Beer, 9 Stefan Ungerer (captain), 8 Carl Els, 7 Stefan Willemse, 6 Gideon van der Merwe, 5 Cameron Lindsay, 4 Ewan Coetzee, 3 Tijde Visser, 2 Alandre van Rooyen, 1 Mox Mxoli. Replacements (from): 16 HJ Luus, 17 Andrew Beerwinkel, 18 John-Roy Jenkinson, 19 Mzwanele Zito, 20 Adre Smith, 21 Ashlon Davids, 22 Johnathan Francke, 23 James Verity-Amm, 24 Bandisa Ndlovu, 25 Raegan Oranje, 26 Harlon Klaasen.