The Capetonians overtook over the Lions, who suffered a surprise 61-30 loss to the Cell C Sharks in Durban, to take top spot on the log.
In the weekend's remaining fixture, the Leopards outplayed Eastern Province by 43-23 in Potchefstroom for their second win in a row. The Vodacom Bulls had a bye.
As a result of the weekend’s action, DHL WP improved their points tally to 14 points from their three wins so far this season. They head the league table on a healthier points' difference from the Lions.
DHL WP scored six tries on their way to a dominant victory over the Toyota Cheetahs at City Park on Saturday. Three tries in each half saw the hosts claim what was ultimately a comfortable bonus point victory that saw them return to winning ways after their narrow defeat to the Lions in Johannesburg in the previous round.
The Vodacom Bulls are sitting in third spot with 12 points from two wins out of three games, while the Leopards increased their league tally to 10 points as a result of their second successive win.
Their big win of 61-30 over the strong Lions outfit lifted the Cell C Sharks to eight points and fifth spot on the log.
Unfortunately for the Toyota Cheetahs, they fell to sixth on the table following their second loss in three match and the young Free Staters have so five collected six points.
EP complete the standings in seventh place and the Eastern Cape youngsters are still looking for their first win and first league points after suffering their third straight loss in Potchefstroom.
Weekend fixtures (home team first):
Friday, 25 March:
Toyota Cheetahs vs Cell C Sharks
Saturday, 26 March:
Lions vs Vodacom Bulls
EP vs DHL WP