The relationship has been developed as part of World Rugby’s international player welfare campaign aimed at supporting the identification and treatment of concussion in rugby.

Marker’s CE-certified concussion test is based on the analysis of small non-coding RNA (sncRNA) biomarkers in the saliva. Marker analyses changes in sncRNA to provide an objective and biological assessment following a suspected concussion event.

Through the collaboration, Marker has provided all teams with access to its CE certified saliva concussion diagnostic test. This includes all players having had baseline saliva testing during pre-season, with additional saliva swabs then taken and assessed for changes in concussion biomarker profiles when a concussive incident was suspected during the season as part of the Head Impact Assessment (HIA) process.

Additionally, Marker has also received salivary swabs from all players fitted with an instrumented mouthguard at the end of each game throughout the season.

“We are delighted to be collaborating with Marker, an innovative leader in the field of biological concussion diagnosis, as we continue to improve safety and brain welfare for the benefit of players at all levels of the game in South Africa,” said Clint Readhead, SA Rugby’s Senior Medical Manager.

“The health and wellbeing of our players in the Currie Cup and throughout our community is of utmost importance and we will continue to do all we can to contribute to better understand and manage this complex injury.”

The data and insight collected is being used by World Rugby, SA Rugby and Marker to evaluate and support appropriate adoption and further research into the continued development of salivary concussion testing for appropriate head injury diagnosis, management, and improve where we can on the graduated return to play protocols.

The initial phase of this initiative between Marker, World Rugby and SA Rugby, which features as part of World Rugby’s evidence based, innovative and technology-driven approach to player brain welfare, will come to a conclusion following the Currie Cup final in Bloemfontein, where the Airlink Pumas will be defending their title against the Toyota Cheetahs.

Additional refinements will continue to be undertaken in other collaborations next season and beyond.

In addition to the Currie Cup, Marker is also working with several partners across men’s and women’s rugby, including Premiership and Allianz Premier 15s teams in England, the Vodacom United Rugby Championship, the recent TikTok Women’s Six Nations, as well as successful data collection during last year’s delayed 2021 Women’s World Cup in New Zealand.

David Cohen, Chairman of Marker, said: “Across all ages and levels of the game, concussion has been – and remains – challenging to diagnose for a number of reasons without the objective test we are currently deploying. In addition to accurate diagnosis of concussion, challenges in assessment continue throughout the return to play process.

“Collaborations such as the ones we have enjoyed with SA Rugby and the English RFU will provide accurate data and insight for medical teams, enabling them to support players with the individualised care they need to make a full brain recovery.”